More on Science
Laura Sanders
3 years ago
Xenobots, tiny living machines, can duplicate themselves.
Strange and complex behavior of frog cell blobs
A xenobot “parent,” shaped like a hungry Pac-Man (shown in red false color), created an “offspring” xenobot (green sphere) by gathering loose frog cells in its opening.
Tiny “living machines” made of frog cells can make copies of themselves. This newly discovered renewal mechanism may help create self-renewing biological machines.
According to Kirstin Petersen, an electrical and computer engineer at Cornell University who studies groups of robots, “this is an extremely exciting breakthrough.” She says self-replicating robots are a big step toward human-free systems.
Researchers described the behavior of xenobots earlier this year (SN: 3/31/21). Small clumps of skin stem cells from frog embryos knitted themselves into small spheres and started moving. Cilia, or cellular extensions, powered the xenobots around their lab dishes.
The findings are published in the Proceedings of the National Academy of Sciences on Dec. 7. The xenobots can gather loose frog cells into spheres, which then form xenobots.
The researchers call this type of movement-induced reproduction kinematic self-replication. The study's coauthor, Douglas Blackiston of Tufts University in Medford, Massachusetts, and Harvard University, says this is typical. For example, sexual reproduction requires parental sperm and egg cells. Sometimes cells split or budded off from a parent.
“This is unique,” Blackiston says. These xenobots “find loose parts in the environment and cobble them together.” This second generation of xenobots can move like their parents, Blackiston says.
The researchers discovered that spheroid xenobots could only produce one more generation before dying out. The original xenobots' shape was predicted by an artificial intelligence program, allowing for four generations of replication.
A C shape, like an openmouthed Pac-Man, was predicted to be a more efficient progenitor. When improved xenobots were let loose in a dish, they began scooping up loose cells into their gaping “mouths,” forming more sphere-shaped bots (see image below). As many as 50 cells clumped together in the opening of a parent to form a mobile offspring. A xenobot is made up of 4,000–6,000 frog cells.
Petersen likes the Xenobots' small size. “The fact that they were able to do this at such a small scale just makes it even better,” she says. Miniature xenobots could sculpt tissues for implantation or deliver therapeutics inside the body.
Beyond the xenobots' potential jobs, the research advances an important science, says study coauthor and Tufts developmental biologist Michael Levin. The science of anticipating and controlling the outcomes of complex systems, he says.
“No one could have predicted this,” Levin says. “They regularly surprise us.” Researchers can use xenobots to test the unexpected. “This is about advancing the science of being less surprised,” Levin says.
Jamie Ducharme
3 years ago
How monkeypox spreads (and doesn't spread)
Monkeypox was rare until recently. In 2005, a research called a cluster of six monkeypox cases in the Republic of Congo "the longest reported chain to date."
That's changed. This year, over 25,000 monkeypox cases have been reported in 83 countries, indicating widespread human-to-human transmission.
What spreads monkeypox? Monkeypox transmission research is ongoing; findings may change. But science says...
Most cases were formerly animal-related.
According to the WHO, monkeypox was first diagnosed in an infant in the DRC in 1970. After that, instances were infrequent and often tied to animals. In 2003, 47 Americans contracted rabies from pet prairie dogs.
In 2017, Nigeria saw a significant outbreak. NPR reported that doctors diagnosed young guys without animal exposure who had genital sores. Nigerian researchers highlighted the idea of sexual transmission in a 2019 study, but the theory didn't catch on. “People tend to cling on to tradition, and the idea is that monkeypox is transmitted from animals to humans,” explains research co-author Dr. Dimie Ogoina.
Most monkeypox cases are sex-related.
Human-to-human transmission of monkeypox occurs, and sexual activity plays a role.
Joseph Osmundson, a clinical assistant professor of biology at NYU, says most transmission occurs in queer and gay sexual networks through sexual or personal contact.
Monkeypox spreads by skin-to-skin contact, especially with its blister-like rash, explains Ogoina. Researchers are exploring whether people can be asymptomatically contagious, but they are infectious until their rash heals and fresh skin forms, according to the CDC.
A July research in the New England Journal of Medicine reported that of more than 500 monkeypox cases in 16 countries as of June, 95% were linked to sexual activity and 98% were among males who have sex with men. WHO Director-General Tedros Adhanom Ghebreyesus encouraged males to temporarily restrict their number of male partners in July.
Is monkeypox a sexually transmitted infection (STI)?
Skin-to-skin contact can spread monkeypox, not simply sexual activities. Dr. Roy Gulick, infectious disease chief at Weill Cornell Medicine and NewYork-Presbyterian, said monkeypox is not a "typical" STI. Monkeypox isn't a STI, claims the CDC.
Most cases in the current outbreak are tied to male sexual behavior, but Osmundson thinks the virus might also spread on sports teams, in spas, or in college dorms.
Can you get monkeypox from surfaces?
Monkeypox can be spread by touching infected clothing or bedding. According to a study, a U.K. health care worker caught monkeypox in 2018 after handling ill patient's bedding.
Angela Rasmussen, a virologist at the University of Saskatchewan in Canada, believes "incidental" contact seldom distributes the virus. “You need enough virus exposure to get infected,” she says. It's conceivable after sharing a bed or towel with an infectious person, but less likely after touching a doorknob, she says.
Dr. Müge evik, a clinical lecturer in infectious diseases at the University of St. Andrews in Scotland, says there is a "spectrum" of risk connected with monkeypox. "Every exposure isn't equal," she explains. "People must know where to be cautious. Reducing [sexual] partners may be more useful than cleaning coffee shop seats.
Is monkeypox airborne?
Exposure to an infectious person's respiratory fluids can cause monkeypox, but the WHO says it needs close, continuous face-to-face contact. CDC researchers are still examining how often this happens.
Under precise laboratory conditions, scientists have shown that monkeypox can spread via aerosols, or tiny airborne particles. But there's no clear evidence that this is happening in the real world, Rasmussen adds. “This is expanding predominantly in communities of males who have sex with men, which suggests skin-to-skin contact,” she explains. If airborne transmission were frequent, she argues, we'd find more occurrences in other demographics.
In the shadow of COVID-19, people are worried about aerosolized monkeypox. Rasmussen believes the epidemiology is different. Different viruses.
Can kids get monkeypox?
More than 80 youngsters have contracted the virus thus far, mainly through household transmission. CDC says pregnant women can spread the illness to their fetus.
Among the 1970s, monkeypox predominantly affected children, but by the 2010s, it was more common in adults, according to a February study. The study's authors say routine smallpox immunization (which protects against monkeypox) halted when smallpox was eradicated. Only toddlers were born after smallpox vaccination halted decades ago. More people are vulnerable now.
Schools and daycares could become monkeypox hotspots, according to pediatric instances. Ogoina adds this hasn't happened in Nigeria's outbreaks, which is encouraging. He says, "I'm not sure if we should worry." We must be careful and seek evidence.
Bob Service
3 years ago
Did volcanic 'glasses' play a role in igniting early life?
Quenched lava may have aided in the formation of long RNA strands required by primitive life.
It took a long time for life to emerge. Microbes were present 3.7 billion years ago, just a few hundred million years after the 4.5-billion-year-old Earth had cooled enough to sustain biochemistry, according to fossils, and many scientists believe RNA was the genetic material for these first species. RNA, while not as complicated as DNA, would be difficult to forge into the lengthy strands required to transmit genetic information, raising the question of how it may have originated spontaneously.
Researchers may now have a solution. They demonstrate how basaltic glasses assist individual RNA letters, also known as nucleoside triphosphates, join into strands up to 200 letters long in lab studies. The glasses are formed when lava is quenched in air or water, or when melted rock generated by asteroid strikes cools rapidly, and they would have been plentiful in the early Earth's fire and brimstone.
The outcome has caused a schism among top origin-of-life scholars. "This appears to be a great story that finally explains how nucleoside triphosphates react with each other to create RNA strands," says Thomas Carell, a scientist at Munich's Ludwig Maximilians University. However, Harvard University's Jack Szostak, an RNA expert, says he won't believe the results until the study team thoroughly describes the RNA strands.
Researchers interested in the origins of life like the idea of a primordial "RNA universe" since the molecule can perform two different functions that are essential for life. It's made up of four chemical letters, just like DNA, and can carry genetic information. RNA, like proteins, can catalyze chemical reactions that are necessary for life.
However, RNA can cause headaches. No one has yet discovered a set of plausible primordial conditions that would cause hundreds of RNA letters—each of which is a complicated molecule—to join together into strands long enough to support the intricate chemistry required to kick-start evolution.
Basaltic glasses may have played a role, according to Stephen Mojzsis, a geologist at the University of Colorado, Boulder. They're high in metals like magnesium and iron, which help to trigger a variety of chemical reactions. "Basaltic glass was omnipresent on Earth at the time," he adds.
He provided the Foundation for Applied Molecular Evolution samples of five different basalt glasses. Each sample was ground into a fine powder, sanitized, and combined with a solution of nucleoside triphosphates by molecular biologist Elisa Biondi and her colleagues. The RNA letters were unable to link up without the presence of glass powder. However, when the molecules were mixed with the glass particles, they formed long strands of hundreds of letters, according to the researchers, who published their findings in Astrobiology this week. There was no need for heat or light. Biondi explains, "All we had to do was wait." After only a day, little RNA strands produced, yet the strands continued to grow for months. Jan Paek, a molecular biologist at Firebird Biomolecular Sciences, says, "The beauty of this approach is its simplicity." "Mix the components together, wait a few days, and look for RNA."
Nonetheless, the findings pose a slew of problems. One of the questions is how nucleoside triphosphates came to be in the first place. Recent study by Biondi's colleague Steven Benner suggests that the same basaltic glasses may have aided in the creation and stabilization of individual RNA letters.
The form of the lengthy RNA strands, according to Szostak, is a significant challenge. Enzymes in modern cells ensure that most RNAs form long linear chains. RNA letters, on the other hand, can bind in complicated branching sequences. Szostak wants the researchers to reveal what kind of RNA was produced by the basaltic glasses. "It irritates me that the authors made an intriguing initial finding but then chose to follow the hype rather than the research," Szostak says.
Biondi acknowledges that her team's experiment almost probably results in some RNA branching. She does acknowledge, however, that some branched RNAs are seen in species today, and that analogous structures may have existed before the origin of life. Other studies carried out by the study also confirmed the presence of lengthy strands with connections, indicating that they are most likely linear. "It's a healthy argument," says Dieter Braun, a Ludwig Maximilian University origin-of-life chemist. "It will set off the next series of tests."
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Glorin Santhosh
3 years ago
Start organizing your ideas by using The Second Brain.
Building A Second Brain helps us remember connections, ideas, inspirations, and insights. Using contemporary technologies and networks increases our intelligence.
This approach makes and preserves concepts. It's a straightforward, practical way to construct a second brain—a remote, centralized digital store for your knowledge and its sources.
How to build ‘The Second Brain’
Have you forgotten any brilliant ideas? What insights have you ignored?
We're pressured to read, listen, and watch informative content. Where did the data go? What happened?
Our brains can store few thoughts at once. Our brains aren't idea banks.
Building a Second Brain helps us remember thoughts, connections, and insights. Using digital technologies and networks expands our minds.
Ten Rules for Creating a Second Brain
1. Creative Stealing
Instead of starting from scratch, integrate other people's ideas with your own.
This way, you won't waste hours starting from scratch and can focus on achieving your goals.
Users of Notion can utilize and customize each other's templates.
2. The Habit of Capture
We must record every idea, concept, or piece of information that catches our attention since our minds are fragile.
When reading a book, listening to a podcast, or engaging in any other topic-related activity, save and use anything that resonates with you.
3. Recycle Your Ideas
Reusing our own ideas across projects might be advantageous since it helps us tie new information to what we already know and avoids us from starting a project with no ideas.
4. Projects Outside of Category
Instead of saving an idea in a folder, group it with documents for a project or activity.
If you want to be more productive, gather suggestions.
5. Burns Slowly
Even if you could finish a job, work, or activity if you focused on it, you shouldn't.
You'll get tired and can't advance many projects. It's easier to divide your routine into daily tasks.
Few hours of daily study is more productive and healthier than entire nights.
6. Begin with a surplus
Instead of starting with a blank sheet when tackling a new subject, utilise previous articles and research.
You may have read or saved related material.
7. Intermediate Packets
A bunch of essay facts.
You can utilize it as a document's section or paragraph for different tasks.
Memorize useful information so you can use it later.
8. You only know what you make
We can see, hear, and read about anything.
What matters is what we do with the information, whether that's summarizing it or writing about it.
9. Make it simpler for yourself in the future.
Create documents or files that your future self can easily understand. Use your own words, mind maps, or explanations.
10. Keep your thoughts flowing.
If you don't employ the knowledge in your second brain, it's useless.
Few people exercise despite knowing its benefits.
Conclusion:
You may continually move your activities and goals closer to completion by organizing and applying your information in a way that is results-focused.
Profit from the information economy's explosive growth by turning your specialized knowledge into cash.
Make up original patterns and linkages between topics.
You may reduce stress and information overload by appropriately curating and managing your personal information stream.
Learn how to apply your significant experience and specific knowledge to a new job, business, or profession.
Without having to adhere to tight, time-consuming constraints, accumulate a body of relevant knowledge and concepts over time.
Take advantage of all the learning materials that are at your disposal, including podcasts, online courses, webinars, books, and articles.
Sylvain Saurel
3 years ago
A student trader from the United States made $110 million in one month and rose to prominence on Wall Street.
Genius or lucky?
From the title, you might think I'm selling advertising for a financial influencer, a dubious trading site, or a training organization to attract clients. I'm suspicious. Better safe than sorry.
But not here.
Jake Freeman, 20, made $110 million in a month, according to the Financial Times. At 18, he ran for president. He made his name in markets, not politics. Two years later, he's Wall Street's prince. Interview requests flood the prodigy.
Jake Freeman bought 5 million Bed Bath & Beyond Group shares for $5.5 in July 2022 and sold them for $27 a month later. He thought the stock might double. Since speculation died down, he sold well. The stock fell 40.5% to 11 dollars on Friday, 19 August 2022. On August 22, 2022, it fell 16% to $9.
Smallholders have been buying the stock for weeks and will lose heavily if it falls further. Bed Bath & Beyond is the second most popular stock after Foot Locker, ahead of GameStop and Apple.
Jake Freeman earned $110 million thanks to a significant stock market flurry.
Online broker customers aren't the only ones with jitters. By June 2022, Ken Griffin's Citadel and Stephen Mandel's Lone Pine Capital held nearly a third of the company's capital. Did big managers sell before the stock plummeted?
Recent stock movements (derivatives) and rumors could prompt a SEC investigation.
Jake Freeman wrote to the board of directors after his investment to call for a turnaround, given the company's persistent problems and short sellers. The bathroom and kitchen products distribution group's stock soared in July 2022 due to renewed buying by private speculators, who made it one of their meme stocks with AMC and GameStop.
Second-quarter 2022 results and financial health worsened. He didn't celebrate his miraculous operation in a nightclub. He told a British newspaper, "I'm shocked." His parents dined in New York. He returned to Los Angeles to study math and economics.
Jake Freeman founded Freeman Capital Management with his savings and $25 million from family, friends, and acquaintances. They are the ones who are entitled to the $110 million he raised in one month. Will his investors pocket and withdraw all or part of their profits or will they trust the young prodigy for new stunts on Wall Street?
His operation should attract new clients. Well-known hedge funds may hire him.
Jake Freeman didn't listen to gurus or former traders. At 17, he interned at a quantitative finance and derivatives hedge fund, Volaris. At 13, he began investing with his pharmaceutical executive uncle. All countries have increased their Google searches for the young trader in the last week.
Naturally, his success has inspired resentment.
His success stirs jealousy, and he's attacked on social media. On Reddit, people who lost money on Bed Bath & Beyond, Jake Freeman's fortune, are mourning.
Several conspiracy theories circulate about him, including that he doesn't exist or is working for a Taiwanese amusement park.
If all 20 million American students had the same trading skills, they would have generated $1.46 trillion. Jake Freeman is unique. Apprentice traders' careers are often short, disillusioning, and tragic.
Two years ago, 20-year-old Robinhood client Alexander Kearns committed suicide after losing $750,000 trading options. Great traders start young. Michael Platt of BlueCrest invested in British stocks at age 12 under his grandmother's supervision and made a £30,000 fortune. Paul Tudor Jones started trading before he turned 18 with his uncle. Warren Buffett, at age 10, was discussing investments with Goldman Sachs' head. Oracle of Omaha tells all.
Guillaume Dumortier
2 years ago
Mastering the Art of Rhetoric: A Guide to Rhetorical Devices in Successful Headlines and Titles
Unleash the power of persuasion and captivate your audience with compelling headlines.
As the old adage goes, "You never get a second chance to make a first impression."
In the world of content creation and social ads, headlines and titles play a critical role in making that first impression.
A well-crafted headline can make the difference between an article being read or ignored, a video being clicked on or bypassed, or a product being purchased or passed over.
To make an impact with your headlines, mastering the art of rhetoric is essential. In this post, we'll explore various rhetorical devices and techniques that can help you create headlines that captivate your audience and drive engagement.
tl;dr : Headline Magician will help you craft the ultimate headline titles powered by rhetoric devices
Example with a high-end luxury organic zero-waste skincare brand
✍️ The Power of Alliteration
Alliteration is the repetition of the same consonant sound at the beginning of words in close proximity. This rhetorical device lends itself well to headlines, as it creates a memorable, rhythmic quality that can catch a reader's attention.
By using alliteration, you can make your headlines more engaging and easier to remember.
Examples:
"Crafting Compelling Content: A Comprehensive Course"
"Mastering the Art of Memorable Marketing"
🔁 The Appeal of Anaphora
Anaphora is the repetition of a word or phrase at the beginning of successive clauses. This rhetorical device emphasizes a particular idea or theme, making it more memorable and persuasive.
In headlines, anaphora can be used to create a sense of unity and coherence, which can draw readers in and pique their interest.
Examples:
"Create, Curate, Captivate: Your Guide to Social Media Success"
"Innovation, Inspiration, and Insight: The Future of AI"
🔄 The Intrigue of Inversion
Inversion is a rhetorical device where the normal order of words is reversed, often to create an emphasis or achieve a specific effect.
In headlines, inversion can generate curiosity and surprise, compelling readers to explore further.
Examples:
"Beneath the Surface: A Deep Dive into Ocean Conservation"
"Beyond the Stars: The Quest for Extraterrestrial Life"
⚖️ The Persuasive Power of Parallelism
Parallelism is a rhetorical device that involves using similar grammatical structures or patterns to create a sense of balance and symmetry.
In headlines, parallelism can make your message more memorable and impactful, as it creates a pleasing rhythm and flow that can resonate with readers.
Examples:
"Eat Well, Live Well, Be Well: The Ultimate Guide to Wellness"
"Learn, Lead, and Launch: A Blueprint for Entrepreneurial Success"
⏭️ The Emphasis of Ellipsis
Ellipsis is the omission of words, typically indicated by three periods (...), which suggests that there is more to the story.
In headlines, ellipses can create a sense of mystery and intrigue, enticing readers to click and discover what lies behind the headline.
Examples:
"The Secret to Success... Revealed"
"Unlocking the Power of Your Mind... A Step-by-Step Guide"
🎭 The Drama of Hyperbole
Hyperbole is a rhetorical device that involves exaggeration for emphasis or effect.
In headlines, hyperbole can grab the reader's attention by making bold, provocative claims that stand out from the competition. Be cautious with hyperbole, however, as overuse or excessive exaggeration can damage your credibility.
Examples:
"The Ultimate Guide to Mastering Any Skill in Record Time"
"Discover the Revolutionary Technique That Will Transform Your Life"
❓The Curiosity of Questions
Posing questions in your headlines can be an effective way to pique the reader's curiosity and encourage engagement.
Questions compel the reader to seek answers, making them more likely to click on your content. Additionally, questions can create a sense of connection between the content creator and the audience, fostering a sense of dialogue and discussion.
Examples:
"Are You Making These Common Mistakes in Your Marketing Strategy?"
"What's the Secret to Unlocking Your Creative Potential?"
💥 The Impact of Imperatives
Imperatives are commands or instructions that urge the reader to take action. By using imperatives in your headlines, you can create a sense of urgency and importance, making your content more compelling and actionable.
Examples:
"Master Your Time Management Skills Today"
"Transform Your Business with These Innovative Strategies"
💢 The Emotion of Exclamations
Exclamations are powerful rhetorical devices that can evoke strong emotions and convey a sense of excitement or urgency.
Including exclamations in your headlines can make them more attention-grabbing and shareable, increasing the chances of your content being read and circulated.
Examples:
"Unlock Your True Potential: Find Your Passion and Thrive!"
"Experience the Adventure of a Lifetime: Travel the World on a Budget!"
🎀 The Effectiveness of Euphemisms
Euphemisms are polite or indirect expressions used in place of harsher, more direct language.
In headlines, euphemisms can make your message more appealing and relatable, helping to soften potentially controversial or sensitive topics.
Examples:
"Navigating the Challenges of Modern Parenting"
"Redefining Success in a Fast-Paced World"
⚡Antithesis: The Power of Opposites
Antithesis involves placing two opposite words side-by-side, emphasizing their contrasts. This device can create a sense of tension and intrigue in headlines.
Examples:
"Once a day. Every day"
"Soft on skin. Kill germs"
"Mega power. Mini size."
To utilize antithesis, identify two opposing concepts related to your content and present them in a balanced manner.
🎨 Scesis Onomaton: The Art of Verbless Copy
Scesis onomaton is a rhetorical device that involves writing verbless copy, which quickens the pace and adds emphasis.
Example:
"7 days. 7 dollars. Full access."
To use scesis onomaton, remove verbs and focus on the essential elements of your headline.
🌟 Polyptoton: The Charm of Shared Roots
Polyptoton is the repeated use of words that share the same root, bewitching words into memorable phrases.
Examples:
"Real bread isn't made in factories. It's baked in bakeries"
"Lose your knack for losing things."
To employ polyptoton, identify words with shared roots that are relevant to your content.
✨ Asyndeton: The Elegance of Omission
Asyndeton involves the intentional omission of conjunctions, adding crispness, conviction, and elegance to your headlines.
Examples:
"You, Me, Sushi?"
"All the latte art, none of the environmental impact."
To use asyndeton, eliminate conjunctions and focus on the core message of your headline.
🔮 Tricolon: The Magic of Threes
Tricolon is a rhetorical device that uses the power of three, creating memorable and impactful headlines.
Examples:
"Show it, say it, send it"
"Eat Well, Live Well, Be Well."
To use tricolon, craft a headline with three key elements that emphasize your content's main message.
🔔 Epistrophe: The Chime of Repetition
Epistrophe involves the repetition of words or phrases at the end of successive clauses, adding a chime to your headlines.
Examples:
"Catch it. Bin it. Kill it."
"Joint friendly. Climate friendly. Family friendly."
To employ epistrophe, repeat a key phrase or word at the end of each clause.